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Panos Macheras, Athanassios Iliadis - Modeling in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics: Homogeneous and Heterogeneous Approaches

English | 2006 | Springer | ISBN: 0-387-28178-9 | 446 pages | PDF | 7 MB

This book presents the state of the art in biopharmaceutics, pharmacokinetics, and pharmacodynamics modeling, demonstrating how advanced physical and mathematical methods can expand classical models to cover heterogeneous drug-biological processes and thebangutic effects in the body. The text is divided into four sections: the first explores fundamental concepts like fractals, nonclassical diffusion-kinetics, and nonlinear dynamics; the second focuses on drug dissolution, release, and absorption; the third covers empirical, compartmental, and stochastic pharmacokinetic models; and the fourth examines classical and nonclassical pharmacodynamic models.


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